The Dynamics of Protein Kinase B Regulation during B Cell Antigen Receptor Engagement
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چکیده
منابع مشابه
The Dynamics of Protein Kinase B Regulation during B Cell Antigen Receptor Engagement
This study has used biochemistry and real time confocal imaging of green fluorescent protein (GFP)-tagged molecules in live cells to explore the dynamics of protein kinase B (PKB) regulation during B lymphocyte activation. The data show that triggering of the B cell antigen receptor (BCR) induces a transient membrane localization of PKB but a sustained activation of the enzyme; active PKB is fo...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1999
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.145.7.1511